Učitavanje...

IL-2–Controlled Expression of Multiple T Cell Trafficking Genes and Th2 Cytokines in the Regulatory T Cell-Deficient Scurfy Mice: Implication to Multiorgan Inflammation and Control of Skin and Lung Inflammation

Scurfy (Sf) mice bear a mutation in the Foxp3 transcription factor, lack regulatory T cells (Treg), develop multiorgan inflammation, and die prematurely. The major target organs affected are skin, lungs, and liver. Sf mice lacking the Il2 gene (Sf.Il2(−/−)), despite being devoid of Treg, did not dev...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Sharma, Rahul, Sharma, Poonam R., Kim, Youngchul, Leitinger, Norbert, Lee, Jae K., Fu, Shu Man, Ju, Shyr-Te
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136806/
https://ncbi.nlm.nih.gov/pubmed/21169543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002677
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!