Interactions Crucial for Three-Dimensional Domain Swapping in the HP-RNase Variant PM8

The structural determinants that are responsible for the formation of higher order associations of folded proteins remain unknown. We have investigated the role on the dimerization process of different residues of a domain-swapped dimer human pancreatic ribonuclease variant. This variant is a good m...

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Bibliographic Details
Main Authors: Tubert, Pere, Laurents, Douglas V., Ribó, Marc, Bruix, Marta, Vilanova, Maria, Benito, Antoni
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2011
Subjects:
Protein
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136784/
https://ncbi.nlm.nih.gov/pubmed/21767499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.06.013
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