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Effect of the HDAC inhibitor SNDX-275 on Fas signaling in osteosarcoma cells and the feasibility of its topical application for the treatment of osteosarcoma lung metastases
BACKGROUND: Patients with osteosarcoma (OS) lung metastases have poor response to the salvage therapy. Understanding the mechanisms involved in metastatic process of OS may lead to new effective therapeutic approaches. We previously found that upregulation of Fas receptor by transfecting OS cells wi...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136583/ https://ncbi.nlm.nih.gov/pubmed/21287529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25884 |
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