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Expression of c-FLIP in pulmonary metastases in osteosarcoma patients and human xenografts

OBJECTIVE(S): We have previously shown that Fas expression inversely correlates with the metastatic potential of osteosarcoma (OS) to the lung. FasL is constitutively expressed in the lung microenvironment and eliminates Fas(+) osteosarcoma cells leaving Fas(−) cells to form metastases. Absence of F...

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Autors principals: Rao-Bindal, Krithi, Rao, Chethan K., Yu, Ling, Kleinerman, Eugenie S.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883385/
https://ncbi.nlm.nih.gov/pubmed/23255321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24412
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