Loading...
Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes
Cell division, membrane rigidity, and strong adhesion to a rigid matrix are all promoted by myosin-II, and so multinucleated cells with distended membranes—typical of megakaryocytes (MKs)—seem predictable for low myosin activity in cells on soft matrices. Paradoxically, myosin mutations lead to defe...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136287/ https://ncbi.nlm.nih.gov/pubmed/21709232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017474108 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|