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Overlapping activation-induced cytidine deaminase hotspot motifs in Ig class-switch recombination
Ig class-switch recombination (CSR) is directed by the long and repetitive switch regions and requires activation-induced cytidine deaminase (AID). One of the conserved switch-region sequence motifs (AGCT) is a preferred site for AID-mediated DNA-cytosine deamination. By using somatic gene targeting...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136278/ https://ncbi.nlm.nih.gov/pubmed/21709240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018726108 |
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