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Adeno-Associated Virus Gene Repair Corrects a Mouse Model of Hereditary Tyrosinemia In Vivo

Adeno-associated virus (AAV) vectors are ideal for performing gene repair due to their ability to target multiple different genomic loci, low immunogenicity, capability to achieve targeted and stable expression through integration, and low mutagenic and oncogenic potential. However, many handicaps t...

詳細記述

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書誌詳細
主要な著者: Paulk, Nicole K., Wursthorn, Karsten, Wang, Zhongya, Finegold, Milton J., Kay, Mark A., Grompe, Markus
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136243/
https://ncbi.nlm.nih.gov/pubmed/20162619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23481
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