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A role for the primary cilium in Notch signaling and epidermal differentiation during skin development
Ciliogenesis precedes lineage-determining signaling in skin development. To understand why, we performed shRNA-mediated knockdown of seven intraflagellar-transport-proteins (IFTs), and conditional ablation of Ift-88 and Kif3a during embryogenesis. Both in cultured keratinocytes and embryonic epiderm...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135909/ https://ncbi.nlm.nih.gov/pubmed/21703454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.05.030 |
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