Protein-RNA and Protein-Protein Recognition by Dual KH1/2 Domains of the Neuronal Splicing Factor Nova-1

Nova onconeural antigens are neuron-specific RNA-binding proteins implicated in paraneoplastic opsoclonus-myoclonus-ataxia (POMA) syndrome. Nova harbors three K-homology (KH) motifs implicated in alternate splicing regulation of genes involved in inhibitory synaptic transmission. We report the cryst...

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Main Authors: Teplova, Marianna, Malinina, Lucy, Darnell, Jennifer C., Song, Jikui, Lu, Min, Abagyan, Ruben, Musunuru, Kiran, Teplov, Alexei, Burley, Stephen K., Darnell, Robert B., Patel, Dinshaw J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134789/
https://ncbi.nlm.nih.gov/pubmed/21742260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.05.002
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