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Inactivation of Murine Usp1 Results in Genomic Instability and a Fanconi Anemia Phenotype
Fanconi anemia (FA) is a human genetic disease characterized by chromosome instability, cancer predisposition, and cellular hypersensitivity to DNA crosslinking agents. The FA pathway regulates the repair of DNA crosslinks. A critical step in this pathway is the monoubiquitination and deubiquitinati...
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| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3134285/ https://ncbi.nlm.nih.gov/pubmed/19217432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.01.001 |
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