Roles of HAUSP-mediated p53 regulation in central nervous system development

The deubiquitinase HAUSP (herpesvirus-associated ubiquitin-specific protease; also called USP7) has a critical role in regulating the p53-Mdm2 (murine double minute 2) pathway. By using the conventional knockout approach, we previously showed that hausp inactivation leads to early embryonic lethalit...

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Main Authors: Kon, N, Zhong, J, Kobayashi, Y, Li, M, Szabolcs, M, Ludwig, T, Canoll, P D, Gu, W
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
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Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134159/
https://ncbi.nlm.nih.gov/pubmed/21350561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.12
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