The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA

Three-dimensional topology of DNA in the cell nucleus provides a level of transcription regulation beyond the sequence of the linear DNA. To study the relationship between the transcriptional activity and the spatial environment of a gene, we used allele-specific chromosome conformation capture-on-c...

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Autors principals: Splinter, Erik, de Wit, Elzo, Nora, Elphège P., Klous, Petra, van de Werken, Harmen J.G., Zhu, Yun, Kaaij, Lucas J.T., van IJcken, Wilfred, Gribnau, Joost, Heard, Edith, de Laat, Wouter
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134081/
https://ncbi.nlm.nih.gov/pubmed/21690198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.633311
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