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Generation of mice with functional inactivation of talpid3, a gene first identified in chicken

Specification of digit number and identity is central to digit pattern in vertebrate limbs. The classical talpid(3) chicken mutant has many unpatterned digits together with defects in other regions, depending on hedgehog (Hh) signalling, and exhibits embryonic lethality. The talpid(3) chicken has a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bangs, Fiona, Antonio, Nicole, Thongnuek, Peerapat, Welten, Monique, Davey, Megan G., Briscoe, James, Tickle, Cheryll
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133916/
https://ncbi.nlm.nih.gov/pubmed/21750036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.063602
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