The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation

The chicken talpid(3) mutant, with polydactyly and defects in other embryonic regions that depend on hedgehog (Hh) signalling (e.g. the neural tube), has a mutation in KIAA0568. Similar phenotypes are seen in mice and in human syndromes with mutations in genes that encode centrosomal or intraflagell...

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Detalhes bibliográficos
Main Authors: Yin, Yili, Bangs, Fiona, Paton, I. Robert, Prescott, Alan, James, John, Davey, Megan G., Whitley, Paul, Genikhovich, Grigory, Technau, Ulrich, Burt, David W., Tickle, Cheryll
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741201/
https://ncbi.nlm.nih.gov/pubmed/19144723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.028464
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