The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation

The chicken talpid(3) mutant, with polydactyly and defects in other embryonic regions that depend on hedgehog (Hh) signalling (e.g. the neural tube), has a mutation in KIAA0568. Similar phenotypes are seen in mice and in human syndromes with mutations in genes that encode centrosomal or intraflagell...

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Главные авторы: Yin, Yili, Bangs, Fiona, Paton, I. Robert, Prescott, Alan, James, John, Davey, Megan G., Whitley, Paul, Genikhovich, Grigory, Technau, Ulrich, Burt, David W., Tickle, Cheryll
Формат: Artigo
Язык:Inglês
Опубликовано: Company of Biologists 2009
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Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741201/
https://ncbi.nlm.nih.gov/pubmed/19144723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.028464
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