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Generation of mice with functional inactivation of talpid3, a gene first identified in chicken

Specification of digit number and identity is central to digit pattern in vertebrate limbs. The classical talpid(3) chicken mutant has many unpatterned digits together with defects in other regions, depending on hedgehog (Hh) signalling, and exhibits embryonic lethality. The talpid(3) chicken has a...

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Bibliografiske detaljer
Main Authors: Bangs, Fiona, Antonio, Nicole, Thongnuek, Peerapat, Welten, Monique, Davey, Megan G., Briscoe, James, Tickle, Cheryll
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133916/
https://ncbi.nlm.nih.gov/pubmed/21750036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.063602
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