Generation of mice with functional inactivation of talpid3, a gene first identified in chicken

Specification of digit number and identity is central to digit pattern in vertebrate limbs. The classical talpid(3) chicken mutant has many unpatterned digits together with defects in other regions, depending on hedgehog (Hh) signalling, and exhibits embryonic lethality. The talpid(3) chicken has a...

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Bibliographic Details
Main Authors: Bangs, Fiona, Antonio, Nicole, Thongnuek, Peerapat, Welten, Monique, Davey, Megan G., Briscoe, James, Tickle, Cheryll
Format: Artigo
Language:Inglês
Published: Company of Biologists 2011
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133916/
https://ncbi.nlm.nih.gov/pubmed/21750036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.063602
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