The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration

The homeodomain transcription factor Nkx2.2 is essential for pancreatic development and islet cell type differentiation. We have identified Tm4sf4, an L6 domain tetraspanin family member, as a transcriptional target of Nkx2.2 that is greatly upregulated during pancreas development in Nkx2.2(–/–) mic...

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Bibliografische gegevens
Hoofdauteurs: Anderson, Keith R., Singer, Ruth A., Balderes, Dina A., Hernandez-Lagunas, Laura, Johnson, Christopher W., Artinger, Kristin B., Sussel, Lori
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Company of Biologists 2011
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133913/
https://ncbi.nlm.nih.gov/pubmed/21750032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.058693
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