The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration

The homeodomain transcription factor Nkx2.2 is essential for pancreatic development and islet cell type differentiation. We have identified Tm4sf4, an L6 domain tetraspanin family member, as a transcriptional target of Nkx2.2 that is greatly upregulated during pancreas development in Nkx2.2(–/–) mic...

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Библиографические подробности
Главные авторы: Anderson, Keith R., Singer, Ruth A., Balderes, Dina A., Hernandez-Lagunas, Laura, Johnson, Christopher W., Artinger, Kristin B., Sussel, Lori
Формат: Artigo
Язык:Inglês
Опубликовано: Company of Biologists 2011
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Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133913/
https://ncbi.nlm.nih.gov/pubmed/21750032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.058693
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