The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration

The homeodomain transcription factor Nkx2.2 is essential for pancreatic development and islet cell type differentiation. We have identified Tm4sf4, an L6 domain tetraspanin family member, as a transcriptional target of Nkx2.2 that is greatly upregulated during pancreas development in Nkx2.2(–/–) mic...

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Bibliografiske detaljer
Main Authors: Anderson, Keith R., Singer, Ruth A., Balderes, Dina A., Hernandez-Lagunas, Laura, Johnson, Christopher W., Artinger, Kristin B., Sussel, Lori
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2011
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133913/
https://ncbi.nlm.nih.gov/pubmed/21750032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.058693
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