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The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration
The homeodomain transcription factor Nkx2.2 is essential for pancreatic development and islet cell type differentiation. We have identified Tm4sf4, an L6 domain tetraspanin family member, as a transcriptional target of Nkx2.2 that is greatly upregulated during pancreas development in Nkx2.2(–/–) mic...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Company of Biologists
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133913/ https://ncbi.nlm.nih.gov/pubmed/21750032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.058693 |
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