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Replacement of the 3′ untranslated variable region of mosquito-borne dengue virus with that of tick-borne Langat virus does not alter vector specificity

The four major flavivirus clades are transmitted by mosquitoes, ticks, directly between vertebrates or directly between arthropods, respectively, but the molecular determinants of mode of transmission in flaviviruses are unknown. To assess the role of the UTRs in transmission, we generated chimeric...

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Detalhes bibliográficos
Main Authors: Tumban, Ebenezer, Mitzel, Dana N., Maes, Nyree E., Hanson, Christopher T., Whitehead, Stephen S., Hanley, Kathryn A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133702/
https://ncbi.nlm.nih.gov/pubmed/21216984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.026997-0
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