A Selective Inhibitor and Probe of the Cellular Functions of Jumonji C Domain-Containing Histone Demethylases

Histone methylations are important chromatin marks that regulate gene expression, genomic stability, DNA repair, and genomic imprinting. Histone demethylases are the most recent family of histone-modifying enzymes discovered. Here, we report the characterization of a small-molecule inhibitor of Jumo...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Luo, Xuelai, Liu, Yongxiang, Kubicek, Stefan, Myllyharju, Johanna, Tumber, Anthony, Ng, Stanley, Che, Ka Hing, Podoll, Jessica, Heightman, Tom D., Oppermann, Udo, Schreiber, Stuart L., Wang, Xiang
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133600/
https://ncbi.nlm.nih.gov/pubmed/21585201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja201597b
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires