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Heterologous expression of pathogen-specific genes ligA and ligB in the saprophyte Leptospira biflexa confers enhanced adhesion to cultured cells and fibronectin

BACKGROUND: In comparison to other bacterial pathogens, our knowledge of the molecular basis of the pathogenesis of leptospirosis is extremely limited. An improved understanding of leptospiral pathogenetic mechanisms requires reliable tools for functional genetic analysis. Leptospiral immunoglobulin...

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Bibliografiske detaljer
Main Authors: Figueira, Cláudio Pereira, Croda, Julio, Choy, Henry A, Haake, David A, Reis, Mitermayer G, Ko, Albert I, Picardeau, Mathieu
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133549/
https://ncbi.nlm.nih.gov/pubmed/21658265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-11-129
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