Heterologous expression of pathogen-specific genes ligA and ligB in the saprophyte Leptospira biflexa confers enhanced adhesion to cultured cells and fibronectin

BACKGROUND: In comparison to other bacterial pathogens, our knowledge of the molecular basis of the pathogenesis of leptospirosis is extremely limited. An improved understanding of leptospiral pathogenetic mechanisms requires reliable tools for functional genetic analysis. Leptospiral immunoglobulin...

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Main Authors: Figueira, Cláudio Pereira, Croda, Julio, Choy, Henry A, Haake, David A, Reis, Mitermayer G, Ko, Albert I, Picardeau, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133549/
https://ncbi.nlm.nih.gov/pubmed/21658265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-11-129
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