Calcium/calmodulin-dependent protein kinase (CaMK) Iα mediates the macrophage inflammatory response to sepsis

Dysregulated Ca(2+) handling is prevalent during sepsis and postulated to perpetuate the aberrant inflammation underlying subsequent organ dysfunction and death. The signal transduction cascades mediating these processes are unknown. Here, we identify that CaMKIα mediates the Mφ response to LPS in v...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Zhang, Xianghong, Guo, Lanping, Collage, Richard D., Stripay, Jennifer L., Tsung, Allan, Lee, Janet S., Rosengart, Matthew R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Leukocyte Biology 2011
Ämnen:
Spotlight on Leading Edge Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133437/
https://ncbi.nlm.nih.gov/pubmed/21372190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0510286
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk