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Calcium/calmodulin-dependent protein kinase (CaMK) Iα mediates the macrophage inflammatory response to sepsis

Dysregulated Ca(2+) handling is prevalent during sepsis and postulated to perpetuate the aberrant inflammation underlying subsequent organ dysfunction and death. The signal transduction cascades mediating these processes are unknown. Here, we identify that CaMKIα mediates the Mφ response to LPS in v...

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Detalhes bibliográficos
Main Authors: Zhang, Xianghong, Guo, Lanping, Collage, Richard D., Stripay, Jennifer L., Tsung, Allan, Lee, Janet S., Rosengart, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133437/
https://ncbi.nlm.nih.gov/pubmed/21372190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0510286
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