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The USP1/UAF1 Complex Promotes Double-Strand Break Repair through Homologous Recombination

Protein ubiquitination plays a key role in the regulation of a variety of DNA repair mechanisms. Protein ubiquitination is controlled by the coordinate activity of ubiquitin ligases and deubiquitinating enzymes (DUBs). The deubiquitinating enzyme USP1 regulates DNA repair and the Fanconi anemia path...

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Detalhes bibliográficos
Main Authors: Murai, Junko, Yang, Kailin, Dejsuphong, Donniphat, Hirota, Kouji, Takeda, Shunichi, D'Andrea, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133424/
https://ncbi.nlm.nih.gov/pubmed/21482670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05058-11
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