Phenotypes in mTERT(+/−) and mTERT(−/−) Mice Are Due to Short Telomeres, Not Telomere-Independent Functions of Telomerase Reverse Transcriptase

Telomerase is essential for telomere length maintenance. Mutations in either of the two core components of telomerase, telomerase RNA (TR) or the catalytic protein component telomerase reverse transcriptase (TERT), cause the genetic disorders dyskeratosis congenita, pulmonary fibrosis, and other deg...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Strong, Margaret A., Vidal-Cardenas, Sofia L., Karim, Baktiar, Yu, Huimin, Guo, Nini, Greider, Carol W.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2011
विषय:
Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133422/
https://ncbi.nlm.nih.gov/pubmed/21464209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05312-11
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