Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells

The intestinal epithelium is maintained by a population of rapidly cycling (Lgr5(+)) intestinal stem cells (ISCs). It has been postulated, however, that slowly cycling ISCs must also be present in the intestine to protect the genome from accumulating deleterious mutations and to allow for a response...

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Detalhes bibliográficos
Main Authors: Montgomery, Robert K., Carlone, Diana L., Richmond, Camilla A., Farilla, Loredana, Kranendonk, Mariette E. G., Henderson, Daniel E., Baffour-Awuah, Nana Yaa, Ambruzs, Dana M., Fogli, Laura K., Algra, Selma, Breault, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017192/
https://ncbi.nlm.nih.gov/pubmed/21173232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013004108
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