Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells

The intestinal epithelium is maintained by a population of rapidly cycling (Lgr5(+)) intestinal stem cells (ISCs). It has been postulated, however, that slowly cycling ISCs must also be present in the intestine to protect the genome from accumulating deleterious mutations and to allow for a response...

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Autori principali: Montgomery, Robert K., Carlone, Diana L., Richmond, Camilla A., Farilla, Loredana, Kranendonk, Mariette E. G., Henderson, Daniel E., Baffour-Awuah, Nana Yaa, Ambruzs, Dana M., Fogli, Laura K., Algra, Selma, Breault, David T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017192/
https://ncbi.nlm.nih.gov/pubmed/21173232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013004108
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