Phenotypes in mTERT(+/−) and mTERT(−/−) Mice Are Due to Short Telomeres, Not Telomere-Independent Functions of Telomerase Reverse Transcriptase

Telomerase is essential for telomere length maintenance. Mutations in either of the two core components of telomerase, telomerase RNA (TR) or the catalytic protein component telomerase reverse transcriptase (TERT), cause the genetic disorders dyskeratosis congenita, pulmonary fibrosis, and other deg...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Strong, Margaret A., Vidal-Cardenas, Sofia L., Karim, Baktiar, Yu, Huimin, Guo, Nini, Greider, Carol W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2011
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133422/
https://ncbi.nlm.nih.gov/pubmed/21464209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05312-11
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