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Organic Hydroperoxide Resistance Protein and Ergothioneine Compensate for Loss of Mycothiol in Mycobacterium smegmatis Mutants

The mshA::Tn5 mutant of Mycobacterium smegmatis does not produce mycothiol (MSH) and was found to markedly overproduce both ergothioneine and an ∼15-kDa protein determined to be organic hydroperoxide resistance protein (Ohr). An mshA(G32D) mutant lacking MSH overproduced ergothioneine but not Ohr. C...

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Hlavní autoři: Ta, Philong, Buchmeier, Nancy, Newton, Gerald L., Rawat, Mamta, Fahey, Robert C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133051/
https://ncbi.nlm.nih.gov/pubmed/21335456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01402-10
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