Organic Hydroperoxide Resistance Protein and Ergothioneine Compensate for Loss of Mycothiol in Mycobacterium smegmatis Mutants

The mshA::Tn5 mutant of Mycobacterium smegmatis does not produce mycothiol (MSH) and was found to markedly overproduce both ergothioneine and an ∼15-kDa protein determined to be organic hydroperoxide resistance protein (Ohr). An mshA(G32D) mutant lacking MSH overproduced ergothioneine but not Ohr. C...

Full description

Saved in:
Bibliographic Details
Main Authors: Ta, Philong, Buchmeier, Nancy, Newton, Gerald L., Rawat, Mamta, Fahey, Robert C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Physiology and Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133051/
https://ncbi.nlm.nih.gov/pubmed/21335456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01402-10
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items