Lack of mycothiol and ergothioneine induces different protective mechanisms in Mycobacterium smegmatis

Mycobacterium smegmatis contains the low molecular weight thiols, mycothiol (MSH) and ergothioneine (ESH). Examination of transposon mutants disrupted in mshC and egtA, involved in the biosynthesis of MSH and ESH respectively, demonstrated that both mutants were sensitive to oxidative, alkylating, a...

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Bibliographic Details
Published in:Biochem Biophys Rep
Main Authors: Singh, Arishma Rajkarnikar, Strankman, Andrew, Orkusyan, Ruzan, Purwantini, Endang, Rawat, Mamta
Format: Artigo
Language:Inglês
Published: Elsevier 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315357/
https://ncbi.nlm.nih.gov/pubmed/28220152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.08.006
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