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A Mycothiol Synthase Mutant of Mycobacterium smegmatis Produces Novel Thiols and Has an Altered Thiol Redox Status

Mycobacteria and other actinomycetes do not produce glutathione but make mycothiol (MSH; AcCys-GlcN-Ins) that has functions similar to those of glutathione and is essential for growth of Mycobacterium tuberculosis. Mycothiol synthase (MshD) catalyzes N acetylation of Cys-GlcN-Ins to produce MSH in M...

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Detalhes bibliográficos
Main Authors: Newton, Gerald L., Ta, Philong, Fahey, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1272995/
https://ncbi.nlm.nih.gov/pubmed/16237013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.21.7309-7316.2005
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