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The EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegans
E3 ubiquitin ligases target a growing number of pro- and anti-apoptotic proteins, including tumour suppressor p53, caspases, and the Bcl-2 family. The core apoptosis pathway is well conserved between mammals and Caenorhabditis elegans, but the extent to which ubiquitin ligases regulate apoptotic cel...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131952/ https://ncbi.nlm.nih.gov/pubmed/21233842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.180 |
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