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Autophagy of germ-granule components, PGL-1 and PGL-3, contributes to DNA damage-induced germ cell apoptosis in C. elegans

Germ granules, termed P granules in nematode C. elegans, are the germline-specific cytoplasmic structures widely observed from worms to humans. P granules are known to have critical functions for postembryonic germline development likely through regulating RNA metabolism. They are localized at the p...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Min, Hyemin, Lee, Yong-Uk, Shim, Yhong-Hee, Kawasaki, Ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534287/
https://ncbi.nlm.nih.gov/pubmed/31125345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008150
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