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The EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegans

E3 ubiquitin ligases target a growing number of pro- and anti-apoptotic proteins, including tumour suppressor p53, caspases, and the Bcl-2 family. The core apoptosis pathway is well conserved between mammals and Caenorhabditis elegans, but the extent to which ubiquitin ligases regulate apoptotic cel...

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Detalhes bibliográficos
Main Authors: Ross, A J, Li, M, Yu, B, Gao, M X, Derry, W B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131952/
https://ncbi.nlm.nih.gov/pubmed/21233842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.180
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