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Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy
The sphingolipid metabolites ceramide and sphingosine-1-phosphate (S1P) have recently been implicated in autophagy. In this study, we report that depletion of sphingosine-1-phosphate phosphohydrolase-1 (SPP1), an endoplasmic reticulum (ER)-resident enzyme that specifically dephosphorylates S1P, indu...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131882/ https://ncbi.nlm.nih.gov/pubmed/20798685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.104 |
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