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Role of Sphingosine-1-Phosphate Phosphohydrolase 1 in the Regulation of Resistance Artery Tone

Sphingosine-1-phosphate (S1P), which mediates pleiotropic actions within the vascular system, is a prominent regulator of microvascular tone. By virtue of its S1P-degrading function, we hypothesized that S1P-phosphohydrolase 1 (SPP1) is an important regulator of tone in resistance arteries. Hamster...

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Detalhes bibliográficos
Main Authors: Peter, Bernhard Friedrich, Lidington, Darcy, Harada, Aki, Bolz, Hanno Jörn, Vogel, Lukas, Heximer, Scott, Spiegel, Sarah, Pohl, Ulrich, Bolz, Steffen-Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746908/
https://ncbi.nlm.nih.gov/pubmed/18583713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.173575
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