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E2F-1 regulation by an unusual DNA damage-responsive DP partner subunit
E2F activity is negatively regulated by retinoblastoma protein (pRb) through binding to the E2F-1 subunit. Within the E2F heterodimer, DP proteins are E2F partner subunits that allow proper cell cycle progression. In contrast to the other DP proteins, the newest member of the family, DP-4, downregul...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131880/ https://ncbi.nlm.nih.gov/pubmed/20559320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.70 |
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