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DNA-damage-responsive acetylation of pRb regulates binding to E2F-1
The pRb (retinoblastoma protein) tumour suppressor protein has a crucial role in regulating the G1- to S-phase transition, and its phosphorylation by cyclin-dependent kinases is an established and important mechanism in controlling pRb activity. In addition, the targeted acetylation of lysine (K) re...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1369245/ https://ncbi.nlm.nih.gov/pubmed/16374512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400591 |
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