14-3-3 proteins integrate E2F activity with the DNA damage response

The E2F family is composed of at least eight E2F and two DP subunits, which in cells exist as E2F/DP heterodimers that bind to and regulate E2F target genes. While DP-1 is an essential and widespread component of E2F, much less is known about the DP-3 subunit, which exists as a number of distinct pr...

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Bibliographic Details
Main Authors:	Milton, Alasdair H, Khaire, Nandkumar, Ingram, Laura, O'donnell, Amanda J, La Thangue, Nicholas B
Format:	Artigo
Language:	Inglês
Published:	2006
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1409719/ https://ncbi.nlm.nih.gov/pubmed/16482218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600999
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14-3-3 proteins integrate E2F activity with the DNA damage response

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