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E2F-1 regulation by an unusual DNA damage-responsive DP partner subunit

E2F activity is negatively regulated by retinoblastoma protein (pRb) through binding to the E2F-1 subunit. Within the E2F heterodimer, DP proteins are E2F partner subunits that allow proper cell cycle progression. In contrast to the other DP proteins, the newest member of the family, DP-4, downregul...

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Autors principals: Ingram, L, Munro, S, Coutts, A S, La Thangue, N B
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131880/
https://ncbi.nlm.nih.gov/pubmed/20559320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.70
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