Ciglitazone negatively regulates CXCL1 signaling through MITF to suppress melanoma growth

We have previously demonstrated that the thiazolidinedione ciglitazone inhibited, independently of PPARγ activation, melanoma cell growth. Further investigations now show that ciglitazone effects are mediated through the regulation of secreted factors. Q-PCR screening of several genes involved in me...

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Bibliografiske detaljer
Main Authors: Botton, T, Puissant, A, Cheli, Y, Tomic, T, Giuliano, S, Fajas, L, Deckert, M, Ortonne, J-P, Bertolotto, C, Tartare-Deckert, S, Ballotti, R, Rocchi, S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131866/
https://ncbi.nlm.nih.gov/pubmed/20596077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.75
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