The cleavage of microphthalmia-associated transcription factor, MITF, by caspases plays an essential role in melanocyte and melanoma cell apoptosis

Microphthalmia-associated transcription factor (MITF) M-form is a melanocyte-specific transcription factor that plays a key role in melanocyte development, survival, and differentiation. Here, we identified MITF as a new substrate of caspases and we characterized the cleavage site after Asp 345 in t...

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Detalhes bibliográficos
Main Authors: Larribere, Lionel, Hilmi, Caroline, Khaled, Mehdi, Gaggioli, Cédric, Bille, Karine, Auberger, Patrick, Ortonne, Jean Paul, Ballotti, Robert, Bertolotto, Corine
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1199569/
https://ncbi.nlm.nih.gov/pubmed/16140982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.335905
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