Spleen tyrosine kinase functions as a tumor suppressor in melanoma cells by inducing senescence-like growth arrest

Loss of tumor suppressive pathways that control cellular senescence is a crucial step in malignant transformation. Spleen tyrosine kinase (Syk) is a cytoplasmic tyrosine kinase that has been recently implicated in tumor suppression of melanoma, a deadly skin cancer deriving from pigments-producing m...

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Detalhes bibliográficos
Main Authors: Bailet, Olivier, Fenouille, Nina, Abbe, Patricia, Robert, Guillaume, Rocchi, Stéphane, Gonthier, Nadège, Denoyelle, Christophe, Ticchioni, Michel, Ortonne, Jean-Paul, Ballotti, Robert, Deckert, Marcel, Tartare-Deckert, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Cancer Research 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855343/
https://ncbi.nlm.nih.gov/pubmed/19293188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2690
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