Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma

Identification and functional validation of oncogenic drivers are essential steps toward advancing cancer precision medicine. Here, we have presented a comprehensive analysis of the somatic genomic landscape of the widely used BRAF(V600E)- and NRAS(Q61K)-driven mouse models of melanoma. By integrati...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Olvedy, Michael, Tisserand, Julie C., Luciani, Flavie, Boeckx, Bram, Wouters, Jasper, Lopez, Sophie, Rambow, Florian, Aibar, Sara, Thienpont, Bernard, Barra, Jasmine, Köhler, Corinna, Radaelli, Enrico, Tartare-Deckert, Sophie, Aerts, Stein, Dubreuil, Patrice, van den Oord, Joost J., Lambrechts, Diether, De Sepulveda, Paulo, Marine, Jean-Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451227/
https://ncbi.nlm.nih.gov/pubmed/28463229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI91291
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