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Metformin inhibits melanoma development through autophagy and apoptosis mechanisms

Metformin is the most widely used antidiabetic drug because of its proven efficacy and limited secondary effects. Interestingly, recent studies have reported that metformin can block the growth of different tumor types. Here, we show that metformin exerts antiproliferative effects on melanoma cells,...

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Detalhes bibliográficos
Main Authors: Tomic, T, Botton, T, Cerezo, M, Robert, G, Luciano, F, Puissant, A, Gounon, P, Allegra, M, Bertolotto, C, Bereder, J-M, Tartare-Deckert, S, Bahadoran, P, Auberger, P, Ballotti, R, Rocchi, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186904/
https://ncbi.nlm.nih.gov/pubmed/21881601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.86
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