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Functional characterization of a SUMO deconjugating protease of Plasmodium falciparum using newly identified small molecule inhibitors

Small ubiquitin-related modifier (SUMO) is implicated in the regulation of numerous biological processes including transcription, protein localization, and cell cycle control. Protein modification by SUMO is found in Plasmodium falciparum; however, its role in the regulation of the parasite lifecycl...

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Hlavní autoři: Ponder, Elizabeth L., Albrow, Victoria E., Leader, Brittany A., Békés, Miklós, Mikolajczyk, Jowita, Fonović, Urša Pečar, Shen, Aimee, Drag, Marcin, Xiao, Junpeng, Deu, Edgar, Campbell, Amy J., Powers, James C., Salvesen, Guy S., Bogyo, Matthew
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131532/
https://ncbi.nlm.nih.gov/pubmed/21700207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.04.010
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